NCT01801592

Obstructive Sleep Apnoea in Patients With Intermittent Claudication

Prevalence of Obstructive Sleep Apnoea in Patients With Intermittent Claudication

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 140 (actual)
• Sponsor: University Hospital, Angers · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main aim of this study is to determine how common undiagnosed obstructive sleep apnoea is in individuals with intermittent claudication.

Detailed description

In patients with peripheral artery disease (PAD), exercise induced limb ischemia (claudication) which limits walking capacity. Symptoms are due to pain at hip and/or buttock. Couple of origins may induce this pain such as vascular, cardiac, respiratory, musculoskeletal, neurologic, hematologic etc. The rate of associated respiratory pathology to patients with lower extremity artery disease (LEAD) is around 15%. The intolerance to walk could be link to an exercise hypoxia which appears with lower limb pain with or without associated dyspnea. The exercise hypoxemia becomes a diagnostic for an intermittent vascular claudication. Tests which are performed to diagnose an intermittent claudication are the Ankle to Brachial Systolic pressure Index (ABI), the echo-Doppler of lower limb arteries and the walking test on a treadmill associated to a measurement of the distal and chest transcutaneous oxygen pressure (tcpO2). Thus, the purpose of the present research is to determine the prevalence of obstructive sleep apnoea in patient with PAD.

Conditions

• Sleep Apnea

Timeline

• Start date: 2013-05-03
• Primary completion: 2017-10-13
• Completion: 2017-10-13
• First posted: 2013-03-01
• Last updated: 2017-11-01

Locations

1 site across 1 country: France