NCT01800097

Treatment of Post Stroke Fatigue With a Wakefulness Promoting Agent

Treatment of Post Stroke Fatigue With Modafinil, Effect on Rehabilitation, Fatigue and Bonemass Index

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Herlev Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study is an investigator initiated placebo controlled double blinded trial. The hypothesis is that treatment with modafinil positively will affect behavioural and cognitive rehabilitation after stroke, causing the treatment group to experience decreased fatigue, increased endurance, improved skills of sustaining attention and faster reaction times. The cognitive rehabilitation will show in increased muscle mass, decreased osteoporosis and better physical performances due to a higher level of physical activity.

Conditions

• Stroke
• Post Stroke Fatigue

Interventions

Type	Name	Description
DRUG	modafinil	Tablet, 400 mg once daily, morning (200 mg if age 65 or above) for 3 months
DRUG	placebo	Tablets, 400 mg once daily ( 200 mg if age 65 or above)morning for 3 months.

Timeline

• Start date: 2012-10-01
• Primary completion: 2015-03-01
• Completion: 2015-03-01
• First posted: 2013-02-27
• Last updated: 2015-06-24

Locations

1 site across 1 country: Denmark