Trials / Completed
CompletedNCT01799564
Micropulse Laser for Geographic Atrophy
A Phase I Study to Establish the Safety and Efficacy of Retinal Pigment Epithelium Micropulse Laser in Subjects With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 11 (actual)
- Sponsor
- Institut de la Macula y la Retina · Academic / Other
- Sex
- All
- Age
- 50 Years
- Healthy volunteers
- Not accepted
Summary
Geographic atrophy (GA) causes the loss of the retinal pigment epithelium (RPE) cells in broad areas of the retina. The application of subthreshold micropulse laser spots in healthy RPE in the vicinity of the area of GA may restore the imbalance in survival factors caused by the disease (ie, the laser may decrease vascular endothelial growth factor and RPE-derived transforming growth factor beta, upregulation of pigment epithelium-derived factor). This may slow or even stop the enlargement of atrophy secondary to GA, and therefore, avoid further vision loss.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Micropulse | Between 1 and 3 sessions of micropulse laser will be applied in the inferior hemiretina of the randomly selected eye |
Timeline
- Start date
- 2012-08-01
- Primary completion
- 2013-11-27
- Completion
- 2013-11-27
- First posted
- 2013-02-27
- Last updated
- 2019-09-18
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT01799564. Inclusion in this directory is not an endorsement.