NCT01799148

Air Pollution, Inflammation and Acute Coronary Syndrome

Impact of AIR Pollution on Inflammation, Oxidative Stress and 1-year Prognosis in Patients Hospitalized for Acute COronary Syndrome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 307 (actual)
• Sponsor: Fundación Canaria Rafael Clavijo para la Investigación Biomédica · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The objectives of this study are: 1) To determine whether patients with acute coronary syndrome, the level of environmental exposure to particulate air pollutants in the week prior to admission, are related to concentrations of inflammatory molecules and oxidative stress. 2) To investigate whether the level of environmental exposure is an independent prognostic factor in terms of overall and cardiovascular mortality, myocardial infarction or unstable angina at 30 days, 6 and 12 months.

Conditions

• Patients With Acute Coronary Syndrome

Interventions

Type	Name	Description
OTHER	Particulate air pollutants	We will determined the average concentrations of different sizes of particulate matter from 1 day or up to 7 days prior to admission in patients with acute coronary syndrome.

Timeline

• Start date: 2011-11-01
• Primary completion: 2014-07-01
• Completion: 2014-11-01
• First posted: 2013-02-26
• Last updated: 2015-01-21

Locations

1 site across 1 country: Spain