NCT01798771

Intraoperative MRI and 5-ALA Guidance to Improve the Extent of Resection in Brain Tumor Surgery

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 108 (estimated)
• Sponsor: Johann Wolfgang Goethe University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators hypothesize that the rate of radiologically complete resections of contrast-enhancing brain tumors following surgeries aided by use of 5-ALA induced fluorescence guidance and use of an intraoperative ultra-low field MRI is higher compared to surgeries aided by 5-ALA induced fluorescene alone.

Conditions

• Primary Malignant Neoplasm of Nervous System
• Glioma
• Glioblastoma
• Metastasis

Interventions

Type	Name	Description
PROCEDURE	Interventional arm	5-ALA fluorescence guided surgery with the additional use of an intraoperative MRI for resection control in patients with contrast enhancing tumors.
PROCEDURE	Control arm	5-ALA fluorescence guided surgery in patients with contrast enhancing tumors.

Timeline

• Start date: 2013-03-01
• Primary completion: 2015-02-01
• Completion: 2016-02-01
• First posted: 2013-02-26
• Last updated: 2013-02-26

Locations

1 site across 1 country: Germany