NCT01794026

Diffusion Weighted Magnetic Resonance Imaging for Preoperative Staging in Gastric Adenocarcinoma Patients

Use of Diffusion Weighted Magnetic Resonance Imaging to Stage Gastric Adenocarcinoma Patients Preoperatively

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Bezmialem Vakif University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Preoperative staging for gastric adenocarcinoma is an important procedure to detect advanced disease stateS for the patients in which the surgery may be unnecessary to perform. Although there are many imaging techniques for this purpose, sensitivity and specificity of these techniques still remains to be low.Preoperative detection of peritoneal carcinomatosis and involvement of lymph nodes beyond D2 may prevent surgical procedures. Removal of the determined lymph nodes according to the type of the surgery is the accepted surgical method. However, accurate determination of malignant lymph nodes may prevent dissection of some groups of the lymph nodes. These findings may cause a new definition of gastric lymph node dissection.

Detailed description

1. proven endoscopic diagnosis of gastric adenocarcinoma 2. for staging purposes, computed tomography for all patients 3. evaluation of benign and malignant lymph nodes according to computed tomography findings and mapping of the lymph nodes 4. to state precisely resectable patients according to computed tomography and anesthetic evaluation 5. evaluation of benign and malignant lymph nodes according to diffusion weighted magnetic resonance imaging findings and mapping of the lymph nodes 6. standard gastrectomy and D2 lymph node dissection 7. mapping of the lymph nodes after taking the specimen out 8. histopathological diagnosis of the lymph nodes and mapping 9. comparison of the results taken from computed tomography, diffusion weighted magnetic resonance imaging and histopathological analysis

Conditions

• Gastric Adenocarcinoma

Interventions

Type	Name	Description
PROCEDURE	diffusion weighted magnetic resonance imaging	for diagnostic purposes, diffusion weighted magnetic resonance imaging in all patients

Timeline

• Start date: 2013-03-01
• Primary completion: 2013-12-01
• Completion: 2013-12-01
• First posted: 2013-02-18
• Last updated: 2017-03-01

Locations

1 site across 1 country: Turkey (Türkiye)