NCT01791998

Magnetic Resonance Thermal Image Guided Laser Interstitial Thermal Therapy in Treating Patients With Breast Cancer

A Pilot Study to Evaluate Magnet Resonance Thermal Imageguided Interstital Thermal Therapy for Focal Ablation of Breast Cancer

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Chicago · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

This pilot clinical trial studies magnetic resonance thermal image guided laser interstitial thermal therapy in treating patients with breast cancer. Magnetic resonance thermal image guided laser interstitial thermal therapy may be able to kill tumor cells by heating up the tumor cells without affecting the surrounding tissue

Detailed description

PRIMARY OBJECTIVES: I. To evaluate the procedural success rate of using the Visualase magnetic resonance (MR)-guided laser system to target, access, thermally monitor, and focally ablate MR-visible breast cancer lesions. 2\. To obtain preliminary data on ablative success using pathologic assessment for specimen excised subsequent to the ablation. OUTLINE: Patients undergo MR-thermal image guided laser interstitial thermal therapy (LITT) over 1 hour. After completion of study treatment, patients are followed up at 3-7 days.

Conditions

• Ductal Breast Carcinoma in Situ
• Invasive Ductal Breast Carcinoma
• Stage IA Breast Cancer
• Stage IB Breast Cancer

Interventions

Type	Name	Description
PROCEDURE	magnetic resonance thermal imaging	Undergo MR-thermal image guided LITT
PROCEDURE	laser interstitial thermal therapy	Undergo MR-thermal image guided LITT

Timeline

• Start date: 2012-08-01
• Primary completion: 2014-06-01
• Completion: 2014-06-01
• First posted: 2013-02-15
• Last updated: 2014-10-15

Locations

1 site across 1 country: United States