Trials / Completed
CompletedNCT01788670
Relevance of the Ethanol Dose in the Generation of Endogenous Hydroxytyrosol
Hydroxytyrosol as an Endogenous and Natural Antioxidant: Modulation by Alcohol Intake. Substudy 1. Evaluating the Relevance of the Ethanol Dose in the Generation of Endogenous Hydroxytyrosol (DOPET).
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 24 (actual)
- Sponsor
- Parc de Salut Mar · Academic / Other
- Sex
- Male
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Accepted
Summary
Health benefits for humans derived from low dose intake of ethanol could partially be explained by its interaction with dopamine (DA) oxidative metabolism. Ethanol is expected to induce an increase in the formation of a DA minor metabolite: DOPET (hydroxytyrosol). Hydroxytyrosol is one of the most potent antioxidants present in Mediterranean Diet. The study is aimed at establishing the contribution of ethanol on hydroxytyrosol formation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Ethanol | |
| OTHER | Water |
Timeline
- Start date
- 2009-05-01
- Primary completion
- 2010-06-01
- Completion
- 2010-06-01
- First posted
- 2013-02-11
- Last updated
- 2013-02-11
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT01788670. Inclusion in this directory is not an endorsement.