NCT01788098

Genetics and Mechanisms of Rheumatoid Arthritis

Rheumatoid Arthritis Susceptibility Genes in Austrian and Slovak Population

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 790 (actual)
• Sponsor: Slovak Academy of Sciences · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The study is aimed at revealing genetic background in rheumatoid arthritis (RA). For that purpose samples of DNA will be collected from 500 RA patients and similar number of controls from whole Slovakia. Variations in several genes associated with RA will be evaluated. The second aim is to assess functional changes in immune cells from selected patients and their evaluation together with genetic background. The project has observational character without any intention to change the treatment of RA patients.

Conditions

• Rheumatoid Arthritis
• Leukocytes, Mononuclear
• Genetic Association Studies

Timeline

• Start date: 2009-10-01
• Primary completion: 2012-06-01
• Completion: 2012-12-01
• First posted: 2013-02-11
• Last updated: 2013-02-11

Locations

1 site across 1 country: Slovakia