NCT01784302

The Effect of Antacids and Multivitamins on Raltegravir

A 3 Arm, 5 Phase Study to Determine the Effect of Divalent and Monovalent Metal Containing Antacids and Multivitamins on the Pharmacokinetics of Raltegravir in Healthy Volunteers

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Helen Reynolds · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

This study seeks to address the question of whether antacids or multivitamins influence the pharmacokinetics of raltegravir when co-administered. The aim of this study is to optimise the dosing of raltegravir when co-administered with antacids or multivitamins.

Conditions

• HIV

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Multivitamins
DIETARY_SUPPLEMENT	Sodium bicarbonate
DRUG	Maalox Plus extra
DRUG	Raltegravir 400 mg

Timeline

• Start date: 2014-04-01
• Primary completion: 2016-02-01
• Completion: 2016-02-01
• First posted: 2013-02-05
• Last updated: 2016-02-25

Locations

1 site across 1 country: United Kingdom