Clinical Trials Directory

Trials / Completed

CompletedNCT01782495

A Study to Evaluate Chronic Hepatitis C Infection in Adult Transplant Recipients

Open-Label, Phase 2 Study to Evaluate the Safety and Efficacy of the Combination of ABT-450/Ritonavir/ABT-267 With ABT-333 and With or Without RBV in HCV Genotype 1 and ABT-450/r/ABT-267 With RBV in HCV GT4-Infected Adult Liver or Renal Transplant Recipients With Hepatitis C Virus (HCV) Infection (CORAL-I)

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
129 (actual)
Sponsor
AbbVie · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the safety and efficacy of ABT-450/r/ABT-267 with or without ABT-333 and with or without ribavirin (RBV) in adult liver or renal transplant recipients with hepatitis C virus (HCV) genotype 1 or 4 (GT1 or GT4) infection.

Conditions

Interventions

TypeNameDescription
DRUGombitasvir/paritaprevir/ritonavir and dasabuvirTablet; ombitasvir coformulated with paritaprevir and ritonavir, dasabuvir tablet
DRUGombitasvir/paritaprevir/ritonavirTablet; ombitasvir coformulated with paritaprevir and ritonavir
DRUGribavirintablet

Timeline

Start date
2013-02-25
Primary completion
2016-11-02
Completion
2017-07-13
First posted
2013-02-04
Last updated
2017-11-07
Results posted
2017-11-07

Source: ClinicalTrials.gov record NCT01782495. Inclusion in this directory is not an endorsement.