Clinical Trials Directory

Trials / Completed

CompletedNCT01777321

Safety and Immunogenicity Study of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine GSK1437173A When Administered Subcutaneously Intramuscularly in Adults Aged ≥50 Years

Safety and Immunogenicity Study of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine GSK1437173A When Administered Subcutaneously Versus Intramuscularly in Adults Aged 50 Years or Older

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
60 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
50 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to assess the immunogenicity, safety, and reactogenicity of GSK Biologicals' Herpes Zoster (HZ) vaccine (GSK 1437173A) when administered subcutaneously (SC) as compared to intramuscularly (IM) to people 50 years of age and older.

Detailed description

There are 2 treatment groups in this study based upon the mode of vaccine administration. The humoral immunogenicity (HI) will be measured in all subjects.

Conditions

Interventions

TypeNameDescription
BIOLOGICALHerpes zoster vaccine GSK1437173AHZ/su vaccine administered either into the subcutaneous tissue of the upper arm (deltoid region) of the non-dominant arm or intramuscularly in the deltoid region of non-dominant arm on a 0,2-month schedule.

Timeline

Start date
2013-06-17
Primary completion
2013-10-10
Completion
2014-11-11
First posted
2013-01-28
Last updated
2018-10-25
Results posted
2017-01-06

Locations

1 site across 1 country: Japan

Source: ClinicalTrials.gov record NCT01777321. Inclusion in this directory is not an endorsement.