NCT01775839

Clinical Trial to Evaluate the Influence of Genotype and DDIs of Aspirin on the PK/PD of Clopidogrel and PK of Digoxin

Clinical Trial to Evaluate the Influence of Genotype of Drug Metabolizing Enzyme or Transporter and Drug-drug Interactions of Aspirin Co-administration on the PK/PD of Clopidogrel and PK of Digoxin in Healthy Volunteers

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: Male
• Age: 20 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Clinical trial to evaluate the influence of multiple aspirin administration on PK and PD of co-administered drugs

Detailed description

Clinical trial to evaluate the influence of genotype of drug metabolizing enzyme or transporter and drug-drug interactions of aspirin co-administration on the pharmacokinetics / pharmacodynamics of clopidogrel and pharmacokinetics of digoxin in healthy volunteers

Conditions

• DRUG REACTIONS

Interventions

Type	Name	Description
DRUG	Aspirin+Clopidogrel/Digoxin(oral)	oral administration of digoxin
DRUG	Aspirin+Clopidogrel/Digoxin(IV)	intravenous administration of digoxin

Timeline

• Start date: 2013-01-01
• Primary completion: 2014-04-01
• Completion: 2014-04-01
• First posted: 2013-01-25
• Last updated: 2014-06-10

Locations

1 site across 1 country: South Korea