NCT01775579

Evaluating a Pharmacokinetic Drug Interaction Between Metformin Hydrochloride and Rosuvastatin Calcium

Randomized, Open Label, Multiple-Dose, 6-sequence, 3-period, Crossover Study to Evaluate a Pharmacokinetic Drug Interaction Between Metformin Hydrochloride and Rosuvastatin Calcium in Healthy Male Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Hanmi Pharmaceutical Company Limited · Industry
• Sex: Male
• Age: 20 Years – 55 Years
• Healthy volunteers: Accepted

Summary

We investigate the potential pharmacokinetic drug-drug interaction between metformin extended release and rosuvastatin in healthy male volunteers who receive metformin extended release alone, rosuvastatin alone, and both together in a 3 period repeatedly.

Conditions

• Diabetes Mellitus

Interventions

Type	Name	Description
DRUG	Glucophage SR tablet 750 mg, Crestor tablet 20 mg

Timeline

• Start date: 2013-01-01
• Primary completion: 2013-03-01
• Completion: 2013-06-01
• First posted: 2013-01-25
• Last updated: 2013-08-23

Locations

1 site across 1 country: South Korea