Clinical Trials Directory

Trials / Terminated

TerminatedNCT01774253

Erivedge (Vismodegib) in the Treatment of Pediatric Patients With Refractory Pontine Glioma

A Phase II, Open-label, Multi-center Study of Erivedge (Vismodegib) in the Treatment of Pediatric Patients With Refractory Pontine Glioma.

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
9 (actual)
Sponsor
Giselle Sholler · Academic / Other
Sex
All
Age
3 Years – 18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this research study is to evaluate an investigational drug (Vismodegib) for Pontine Glioma that is growing or has come back (reoccurred). This study will look at the tumors response to the study drug, Vismodegib, and will also look at the safety and tolerability of Vismodegib. Vismodegib has been tested in multiple adult clinical trials and one pediatric trial. Laboratory testing in pontine gliomas suggests that this drug may be effective in treating this disease.

Conditions

Interventions

TypeNameDescription
DRUGVismodegib

Timeline

Start date
2013-05-01
Primary completion
2015-10-01
Completion
2015-10-01
First posted
2013-01-23
Last updated
2024-08-06
Results posted
2016-10-28

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01774253. Inclusion in this directory is not an endorsement.