NCT01771224

Effect of FAn-7 in UC Activity

Effect of Palmitoleic Acid (FAn-7) on Expression of HNF4γ and Ulcerative Colitis (UC) Activity

• Status: Unknown
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: National Institute of Medical Sciences and Nutrition, Salvador Zubiran · Academic / Other
• Sex: All
• Age: 18 Years – 59 Years
• Healthy volunteers: Not accepted

Summary

Introduction: Inflammatory bowel disease (IBD) refers to two chronic diseases that cause intestinal inflammation, ulcerative colitis (UC) and Crohn's disease (CD). The conventional treatment is not effective; therefore, alternative therapies may be effective specially in UC patients. Fatty acid (FA) may have a beneficial effect on some UC patients. The increasing incidence and prevalence of UC and ineffective treatments in some patients, allows search coadjuvant therapies. Objective: Quantification of differences between patients with and without FA. Methods: In two groups of patients with UC is administered FA and placebo. We will measure the changes clinical, endoscopic and histological in both groups, before and after treatment.

Conditions

• Inflammatory Bowel Disease
• Ulcerative Colitis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Palmitoleic acid	Palmitoleic acid and 5-ASA

Timeline

• Start date: 2013-01-01
• Primary completion: 2013-12-01
• Completion: 2014-12-01
• First posted: 2013-01-18
• Last updated: 2013-01-18

Locations

1 site across 1 country: Mexico