NCT01771055

Direct Peritoneal Resuscitation Effects in the Damage Control Patient

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 7 (actual)
• Sponsor: University of Louisville · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to find if direct peritoneal resuscitation helps blood flow through important organs in a person's body after they have had a traumatic injury with massive blood loss. Sometimes after severe injuries requiring operation, surgeons cannot close the muscles and skin of a patient's belly, because of swelling. This study will also try to find if direct peritoneal resuscitation decreases tissue swelling and allows for quicker closure of of a patient's belly.

Detailed description

Standard methods of controlling bleeding and increasing blood flow to vital organs will be used. These methods include giving blood and fluids and surgically repairing the vessels that are causing the bleeding which are standard ways physicians treat injuries with massive blood loss. A drain (a small plastic tube) will be placed inside the belly. Subjects will randomly (like flipping a coin) be placed into a group of patients who either get a sugar solution dripped into the belly after surgery or do not get this treatment. The drain will be used to drip a high glucose solution into the abdomen in patients be part of that group. The fluid will continue to be dripped into the belly until it is possible to close the skin and underlying layers.

Conditions

• Traumatic Injury

Interventions

Type	Name	Description
PROCEDURE	Galactose	Galactose dripped into the abdomen after surgery
PROCEDURE	Standard surgical methods

Timeline

• Start date: 2012-01-01
• Primary completion: 2016-06-01
• Completion: 2016-06-01
• First posted: 2013-01-18
• Last updated: 2021-06-16
• Results posted: 2021-06-16

Locations

1 site across 1 country: United States