NCT01770444

Low-Dose Coronary Computed Tomographic Angiography for Early Triage of Acute Chest Pain

Safety and Efficacy of Implementing Low-Dose Coronary Computed Tomographic Angiography for Early Triage of Acute Chest Pain in Emergency Department

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 681 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

This study is to see whether the low-dose coronary computed tomographic angiography (CCTA) protocol is as safe and efficacious as conventional-dose protocol in early triage of acute chest pain.

Detailed description

Currently, CCTA is a valuable tool for early triage of low to intermediate risk acute chest pain patients in emergency department. However, it has been criticized for causing unnecessary radiation exposure in the population where its majority has no coronary lesion. A low-dose CCTA protocol comprised with 1) dedicated cardiac imaging protocol (rather than triple rule-out protocol), 2) prospective gating and 3) without additional imaging for calcium scoring will be used to implement the low-dose imaging. We hypothesized that the low-dose CCTA protocol will be as safe and efficacious as conventional dose protocol while decreasing the amount of radiation exposure significantly.

Conditions

• Chest Pain

Interventions

Type	Name	Description
OTHER	Low-dose Cardiac CT protocol	A cardiac CT protocol modified for reduction of radiation exposure 1. Prospective gating 2. Range: dedicated imaging (below carina to heart base)
OTHER	Conventional cardiac CT protocol	Conventional CCTA protocol 1. Retrospective gating with tube current modulation 2. Range: dedicated imaging (below carina to heart base)

Timeline

• Start date: 2012-12-01
• Primary completion: 2016-04-01
• Completion: 2016-04-01
• First posted: 2013-01-17
• Last updated: 2016-11-02

Locations

3 sites across 1 country: South Korea