NCT01765491

Comparison of Two Methods of Bowel Preparation for Colonoscopy in Hospitalized Patients

Comparison of Morning-only With Split-dose Polyethylene Glycol for Colonoscopy Preparation in Hospitalized Patients: A Randomized Controlled Non-Inferiority Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Cook County Health · Other Government
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Morning-only colonoscopy preparation may improve efficiency by allowing same-day patient preparation and colonoscopy. The aim of the investigators study is to compare the efficacy and tolerability of morning-only Polyethylene Glycol (PEG) to split-dose preparation in hospitalized patients undergoing colonoscopy.

Detailed description

This is a single-center, prospective, endoscopist-blinded study in which hospitalized patients scheduled to undergo diagnostic colonoscopy were randomly assigned to receive one gallon of PEG either the morning of colonoscopy or as a split-dose (evening-morning). The primary end point is efficacy of colonoscopy preparation measured by the Ottawa scale. The investigators pre-specified a non-inferiority margin of 1.5 for the difference in Ottawa scale between arms. Secondary end points are patient compliance and tolerance. N: 120 hospitalized patients scheduled for diagnostic colonoscopy.

Conditions

• Bowel Preparation for Colonoscopy

Interventions

Type	Name	Description
OTHER	Split-dose polyethylene glycol	Half gallon of polyethylene glycol to be taken between 7-9 pm on the day before colonoscopy and the remaining half between 7-9 am on the day of colonoscopy
OTHER	Morning-only polyethylene glycol	One gallon of polyethylene glycol to be taken between 5am and 9am on the day of colonoscopy

Timeline

• Start date: 2012-08-01
• Primary completion: 2012-11-01
• Completion: 2012-12-01
• First posted: 2013-01-10
• Last updated: 2023-06-18

Locations

1 site across 1 country: United States