Trials / Completed
CompletedNCT01764555
Pharmacokinetics of Acetaminophen in Morbidly Obese Patients
Pharmacokinetics of Intravenous Acetaminophen and Its Metabolites in Morbidly Obese Patients
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 28 (actual)
- Sponsor
- St. Antonius Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
This study will investigate the pharmacokinetics of acetaminophen in morbidly obese patients versus normal weight patients. Specifically the different metabolic pathways of acetaminophen in morbidly obese adults will be investigated; glucuronidation, sulphation and CYP2E1 (cytochrome P450 2E1) oxidation
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | acetaminophen 2 g |
Timeline
- Start date
- 2012-12-01
- Primary completion
- 2014-03-01
- Completion
- 2014-03-01
- First posted
- 2013-01-09
- Last updated
- 2019-04-05
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT01764555. Inclusion in this directory is not an endorsement.