NCT01763697

Taste Acuity and Caloric Intake After Acute Morphine Administration

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

This study will investigate the effects of acute morphine administration on taste acuity and how much a person eats. It is hypothesized that there will be a dose dependent decrease in taste acuity and dose dependent increase in food intake associated with acute morphine administration. Knowledge from this study will impact the future of feeding behavior and obesity research in the general population. Results will also promote exploration of the long-term effect of opioid abuse on taste acuity and feeding behavior in substance abusing populations.

Conditions

• Taste Sweet
• Taste Salty
• Feeding Behavior

Interventions

Type	Name	Description
BEHAVIORAL	taste acuity assessment	Quantitative measurement of for tasting detection and recognition thresholds, magnitude of perception and hedonic response.
BEHAVIORAL	Recorded meal

Timeline

• Start date: 2013-03-01
• Primary completion: 2014-05-01
• Completion: 2014-05-01
• First posted: 2013-01-09
• Last updated: 2014-05-29

Locations

1 site across 1 country: United States