Trials / Unknown
UnknownNCT01763034
Limb Ischemic Preconditioning for Prevention of Contrast Media Induced Nephropathy in Diabetic Kidney Patient
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- Sponsor
- Ramathibodi Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Contrast media induced nephropathy (CIN) is considered to be a serious complication in patient who underwent coronary angiogram (CAG). The pathogenesis of CIN does not well understood. The probable one is the contrast media makes the afferent vessel in glomeruli constrict and results in renal shut down. Limb ischemic preconditioning, a procedure that makes muscles become ischemic and adapt themselves to produce some cytokines for signaling the vessel more dilated. After the reperfusion, these cytokines are getting back to systemic circulation and effect the afferent vessel in glomeruli to become more dilated and prevent CIN.
Conditions
- Serum Cystatin C Before and After Coronary Angiogram
- Serum Creatinine Before and After Coronary Angiogram
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | limb ischemic preconditioning | use a simple blood pressure cuff inflate for 5 minutes and deflate for 5 minutes alternately in each arms total = 3 cycle in each arm |
Timeline
- Start date
- 2013-02-01
- Primary completion
- 2013-12-01
- Completion
- 2014-03-01
- First posted
- 2013-01-08
- Last updated
- 2013-04-23
Locations
1 site across 1 country: Thailand
Source: ClinicalTrials.gov record NCT01763034. Inclusion in this directory is not an endorsement.