NCT01762176

Early RA MRI Early Intensive Treatment Study

Effect of Early Intensive Treatment in Chinese Patients With Recent-onset Rheumatoid Arthritis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 163 (actual)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

To compare the effectiveness of two treatment strategies in early rheumatoid arthritis (ERA), namely the delayed usual care and early intensive care, in Hong Kong. * The delayed usual care reflects the usual treatment practice in Hong Kong * The early intensive care includes tight monitoring and immediate adjustment of therapy

Detailed description

This study is a 1-year non-randomized clinical trial. Two groups of patients (delayed usual care and early intensive care) with diagnosis of rheumatoid arthritis (RA) and with symptoms onset of less than 2 years and disease modifying anti-rheumatic drugs (DMARDs) naive will be recruited. Remission is reached if patients fulfill the Boolean criteria.

Conditions

• Early Rheumatoid Arthritis

Interventions

Type	Name	Description
PROCEDURE	Protocolized intensive treatment	Intensive treatment is defined as early diagnosis, frequent assessment (monthly) of disease activity that guides treatment change with the aim to achieve clinical remission based on a tight control protocol
PROCEDURE	Usual care	Usual care is defined as treatment decision at the discretion of the rheumatologists and patients reflecting daily clinical practice

Timeline

• Start date: 2012-10-01
• Primary completion: 2018-07-01
• Completion: 2018-07-01
• First posted: 2013-01-07
• Last updated: 2023-09-06

Locations

1 site across 1 country: China