Clinical Trials Directory

Trials / Completed

CompletedNCT01761123

Immunogenicity of Seasonal Influenza by Delivery Directly to Ileum

An Open Label Phase I Substudy to Evaluate the Safety and Ability to Enhance Immunogenicity of VXA-A1.1 by Delivery Directly to the Ileum Using the InteliSite Companion Capsule in Healthy Adult Males

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
37 (actual)
Sponsor
Vaxart · Industry
Sex
Male
Age
18 Years – 49 Years
Healthy volunteers
Accepted

Summary

the purpose of the study is to determine the safety and tolerability of VXA-A1.1, an adjuvanted adenoviral based influenza vaccine, when delivery is targeted to the ileum, using a radio controlled capsule. The secondary objective is to evaluate the immune response (cellular and humoral) of two doses of VXA-A1.1 oral vaccine.

Conditions

Interventions

TypeNameDescription
BIOLOGICALVXA-A1.1

Timeline

Start date
2013-01-01
Primary completion
2014-10-01
Completion
2014-10-01
First posted
2013-01-04
Last updated
2014-12-10

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01761123. Inclusion in this directory is not an endorsement.