NCT01758120

Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy

A Prospective Randomized, Controlled, Open-labeled Trial of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 135 (actual)
• Sponsor: Guangdong Provincial People's Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Treatment of prednisone plus cyclophosphamide may be superior to treatment of prednisone alone in patients with advanced-stage IgA nephropathy.

Conditions

• IgA Nephropathy

Interventions

Type	Name	Description
DRUG	prednisone plus cyclophosphamide	1. prednisone plus cyclophosphamide: prednisone(0.5mg/kg/day\*6 months) plus cyclophosphamide(1g intravenous use,per 1 month\*6months); 2. supportive care,including ACE-I or ARBs and blood pressure control
DRUG	Prednisone alone	1. prednisone alone: prednisone(0.5mg/kg/day\*6 months); 2. supportive care,including ACE-I or ARBs and blood pressure control

Timeline

• Start date: 2012-12-01
• Primary completion: 2019-12-01
• Completion: 2019-12-01
• First posted: 2013-01-01
• Last updated: 2017-07-14

Locations

1 site across 1 country: China