Trials / Unknown
UnknownNCT01757236
Efficacy and Safety Study of Antibiotic Treatment to Treat Hip Prosthetic Joint Infection
Prospective,Randomized,Open Label,European Multicenter Study of the Efficacy of the Linezolid-rifampin Combination Versus Standard of Care in the Treatment of Gram-positive.
- Status
- Unknown
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- Sponsor
- University Hospital, Tours · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to evaluate the efficacy of oral linezolid-rifampin combination therapy (over 4 or 6 weeks) versus the standard of care in the treatment of Gram-positive prosthetic hip joint infection with a one-stage surgical treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | VANCOMYCIN | |
| DRUG | CEFTRIAXONE | |
| DRUG | CLINDAMYCIN | |
| DRUG | SULFAMETHOXAZOLE AND TRIMETHOPRIM (CO-TRIMOXAZOLE) | |
| DRUG | FLUOROQUINOLONE | |
| DRUG | LINEZOLID | |
| DRUG | RIFAMPIN |
Timeline
- Start date
- 2012-10-01
- Primary completion
- 2016-04-01
- Completion
- 2016-04-01
- First posted
- 2012-12-28
- Last updated
- 2014-05-28
Locations
9 sites across 3 countries: France, Italy, Spain
Source: ClinicalTrials.gov record NCT01757236. Inclusion in this directory is not an endorsement.