NCT01754948

Biological Monitoring of Nano Sized Particles in the Airways of Asthmatic Children

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Tel-Aviv Sourasky Medical Center · Other Government
• Sex: All
• Age: 6 Years – 18 Years
• Healthy volunteers: Accepted

Summary

Background Ambient airborne particulate material (PM) is defined according the aerodynamic diameter into coarse, fine, and ultrafine or "nano" sized particles ranging between 2.5-10 µm (coarse), \<2.5 µm (fine), and \<0.1 µm (nano(. Many studies have examined particle effect on respiratory health in children, mainly by environmental monitoring of coarse and fine particles. Biological assessment of individual exposure to nano sized particles in correlation to adverse health effect was not previously studied. Hypothesis individual exposure to nano sized particles in children is associated with reduction in forced expiratory volume at one second.

Conditions

• Asthma

Timeline

• Start date: 2012-07-01
• Primary completion: 2013-06-01
• Completion: 2013-06-01
• First posted: 2012-12-21
• Last updated: 2012-12-21

Locations

1 site across 1 country: Israel