NCT01750528

Prevalence and Progression of Periodontitis in Ankylosing Spondylitis

The Prevalence and the Progression of Periodontitis in Ankylosing Spondylitis (AS) Patients Versus Non-AS Population

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 168 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

1. Our hypotheses on the relationship between periodontitis and AS are as follows; * The prevalence of periodontitis is higher in AS patients group than that of non-AS control group * Anti-TNF-α therapy would favorably affect the disease course of periodontitis. 2. Based on our hypotheses, the specific objectives of the present proposal are as follows; * The primary objective is to compare the prevalence rate of periodontitis between AS patient group and non-AS group. * The secondary objectives will be: * To observe the carriage rate of P. gingivalis in AS and non-AS groups * To identify clinical parameters associated with the severity of periodontitis in AS group. * To compare the progression of periodontitis at weeks 12 and 24 between AS and non-AS groups or between AS patients with and without anti-TNF-α treatment

Conditions

• Ankylosing Spondylitis
• Periodontitis

Timeline

• Start date: 2012-09-01
• Primary completion: 2014-05-01
• Completion: 2014-05-01
• First posted: 2012-12-17
• Last updated: 2014-06-10

Locations

1 site across 1 country: South Korea