NCT01749358

Dose Optimization for Stroke Evaluation

Optimizing the Dose of Rehabilitation After Stroke.

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: University of Southern California · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

This study is about rehabilitation of arm function after a stroke. The investigators are testing the dosage of therapy that is needed for meaningful recovery of arm and hand function. Dosage of therapy refers to the amount of time (in this case, the total number of hours) that a person participates in treatment. The investigators hope to learn how much therapy time is needed in order for change to occur in arm and hand function after a person has had a stroke. Eligible candidates must have had a stroke affecting the use of an arm or hand at least 6 months ago.

Conditions

• Stroke
• Cerebrovascular Disorders
• Brain Ischemia
• Infarction

Interventions

Type	Name	Description
BEHAVIORAL	Accelerated Skill Acquisition Program (ASAP)	A focused, intense, evidence-based, upper extremity rehabilitation program. The training intervention is based on the fundamental elements of skill acquisition through task-specific practice, impairment mitigation to increase capacity, and motivational enhancements to build self-confidence Dosage of therapy (number of hours of therapy) will vary based on group assignment. Frequency is 4x/week, 1 week per month for 3 months in a train-wait-train paradigm. A 2-hour orientation session precedes the first visit.
BEHAVIORAL	Active Monitoring	This is an observation-only group. Any therapy received while in this group will be dosed according to usual and customary practice.

Timeline

• Start date: 2012-03-01
• Primary completion: 2016-08-01
• Completion: 2016-08-01
• First posted: 2012-12-13
• Last updated: 2017-04-06

Locations

1 site across 1 country: United States