NCT01747226

Effect of Mouth Rinses in Oral Malodor

Masking and Therapeutic Effect of Different Mouth Rinses in Patients With Oral Malodor.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 96 (estimated)
• Sponsor: Universitaire Ziekenhuizen KU Leuven · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Bad breath or halitosis is caused by specific gases originating from the mouth or the expired air. In most cases the pathology lies within the mouth and in this case receives the name pathologic halitosis of oral cause or oral malodor. The aim of this study is to evaluate the immediate (masking) and long term (therapeutic) effect of commercially available mouth rinses in the treatment of oral malodor. For this volunteers with oral malodor detected by organoleptic evaluation and confirmed by the increase level of sulphur compounds in their breath (VSC) will be asked to use a designated mouthwash. The breath parameters will be assessed at baseline and 15' after the first rinse (15 ml, during 1 minute) and over night at the end of a period of 3 weeks during which the volunteers rinsed twice a day (15 ml, 1 minute) with the assigned mouthwash. The short and long term effect of a stannous fluoride/amine fluoride/zinc rinse; a chlorhexidine/cetylpyridinium chloride/zinc product and a negative control(fluoride rinse and/or water) will be compared.

Conditions

• Halitosis

Interventions

Type	Name	Description
OTHER	Fluoride rinse	rinse with 15 ml for 1 minute
OTHER	Halita	rinsing with 15 ml for 1 minute
OTHER	Meridol Halitosis	rinsing with 15 ml for 1 minute
OTHER	Water	rinsing with 15ml for 1 minute

Timeline

• Start date: 2013-03-01
• Primary completion: 2015-03-01
• Completion: 2015-12-01
• First posted: 2012-12-11
• Last updated: 2012-12-11

Locations

1 site across 1 country: Belgium