NCT01739868

Screening and Understanding of the Pre-diabetes: DECODIAB

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 103 (actual)
• Sponsor: Nantes University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main objective of the study is to understand the pathophysiological mechanisms involved in switching from pre-diabetes to type 2 diabetes and to identify new biomarkers of type 2 diabetes risk in the population of patients with pre-diabetes.

Conditions

• Pre-diabetes

Interventions

Type	Name	Description
OTHER	Biopsies of muscular and fat tissue	3 half days of metabolic exploration including blood sample, urinary taking, OGTT (oral glucose tolerance test), biopsies of muscular and fat tissue: * 1 visit the first year (inclusion visit) * 1 visit at the end of 5 years of follow-up or in the appearance of type 2 diabetes * 1 intermediary visit (in 3 years) or activated by the following conditions: * Escalation of the glycemia (increase of 0.1g / l of the glycemia and/or 0.3 % of the HbA1c) * Normalization of the glycemia (fasting blood glucose \< 1 g/l)

Timeline

• Start date: 2011-04-01
• Primary completion: 2018-04-01
• Completion: 2018-04-01
• First posted: 2012-12-04
• Last updated: 2015-04-16

Locations

1 site across 1 country: France