NCT01737437

Effect of Lidocaine Sprayed on Hemodynamics During Endotracheal Intubation

Effect of Lidocaine Sprayed on Direct Laryngoscopy and Trachea on Hemodynamics During Endotracheal Intubation

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

A previous study demonstrated topical lidocaine spray on the larynx and the trachea is effective in reducing hemodynamic response to laryngoscopy and endotracheal intubation. In clinical practice, blind oropharyngeal application of lidocaine without aiding direct laryngoscopy can not assured that sprayed lidocaine effectively reaches the larynx and trachea. Therefore, direct laryngoscopy should be necessary to reach topical lidocaine to correct sites. Unfortunately, direct laryngoscopy itself can affect hemodynamics during spraying lidocaine. In this study, we will investigate an effect of lidocaine sprayed on direct laryngoscopy and the tracheal mucosa on hemodynamic change throughout intubation.

Conditions

• Neurosurgical Patients

Interventions

Type	Name	Description
DRUG	group C	0.9% normal saline was applied to trachea and laryngoscope blade
DRUG	group L	10% Lidocaine was applied to the laryngoscope blade and 0.9% normal saline was applied to the trachea.
DRUG	group V	0.9% normal saline was applied to the laryngoscope blade and 10% Lidocaine was applied on trachea.
DRUG	group LV	10% Lidocaine was applied on laryngoscope blade and trachea.

Timeline

• Start date: 2012-10-01
• Primary completion: 2013-01-01
• Completion: 2013-01-01
• First posted: 2012-11-29
• Last updated: 2012-11-29

Locations

1 site across 1 country: South Korea