NCT01734564

Phase II Study With Hiltonol and Dendritic Cells in Solid Tumors

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Clinica Universidad de Navarra, Universidad de Navarra · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In this phase II study, patients with solid tumors will receive treatment with hiltonol and autologous dendritic cells.

Detailed description

In this phase II study, patients with solid tumors will receive treatment with intratumoral hiltonol and two cycles of autologous dendritic cells loaded with autologous tumor and administered subcutaneously. A new cohort will explore the role of radiation therapy, looking for an abscopal effect.

Conditions

• Neoplasms

Interventions

Type	Name	Description
BIOLOGICAL	Hiltonol and autologous dendritic cells	Hiltonol and autologous dendritic cells
RADIATION	Hiltonol, dendritic cells and radiation	Hiltonol, autologous dendritic cells and radiation therapy. Radiation therapy will pursue an abscopal effect.

Timeline

• Start date: 2012-11-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2012-11-27
• Last updated: 2017-04-11

Locations

1 site across 1 country: Spain