NCT01730365

Optical Detection of Malignancy During Percutaneous Interventions

Discrimination of Benign and Malignant Human Tissue During Percutaneous Interventions Using Optical Spectroscopy Techniques

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 104 (actual)
• Sponsor: Philips Healthcare · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Investigation of application possibilities of optical spectroscopy within the field of oncology. Optical spectroscopy enables the possibility to specifically differentiate between different (human) tissues. The hypothesis is that incorporation of this technique into existing medical devices (e.g. biopsy needle) would enlarge the accuracy and reliability of these devices. The purpose is to improve and speed up the diagnostics and therapy of the malignancies.

Detailed description

Primary Objective: In this observational study the investigators aim to evaluate whether optical spectroscopy can correctly diagnose malignant tissue in the existing clinical workflow of percutaneous interventions in lung, liver, and breast. Secondary Objective: During the measurement procedure, possible improvements of the measurement hardware will be recorded. Analysis of this documentation will provide information for possible alterations of hardware design for improved clinical applicability in the future. Special attention will be paid to observe how the procedure fits in the standard workflow of the radiologist.

Conditions

• Pulmonary Coin Lesion
• Colon Cancer Liver Metastasis
• Breast Cancer

Interventions

Type	Name	Description
PROCEDURE	Core biopsy procedure	Core biopsy of suspicious lesion in lung, liver, breast, or colorectal liver metastasis.

Timeline

• Start date: 2012-10-01
• Primary completion: 2015-12-01
• Completion: 2015-12-01
• First posted: 2012-11-21
• Last updated: 2016-04-11

Locations

1 site across 1 country: Netherlands