Trials / Completed
CompletedNCT01729702
Neurohormonal Parameters in Hypertrophic Cardiomyopathies
Evaluation at Rest and Exercise of Clinical, Ultrasonic and Neurohormonal Parameters in Hypertrophic Cardiomyopathies
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 131 (actual)
- Sponsor
- French Cardiology Society · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The primary purpose of this study is to demonstrate that changes in plasma levels of circulating neurohormones (mainly BNP and NT-proBNP), measured at rest and post-exercise correlate with exercise functional limitation (assessed by exercise peak VO2) and exercise ultrasonic parameters (as left ventricular filling, obstruction, and mitral regurgitation)
Detailed description
The secondary purposes are to study the kinetics of secretions of natriuretic peptides, and their relationships with extent of MRI myocardial fibrosis with the degree of exercise functional limitation.
Conditions
- 1- Primary (Sarcomeric) Hypertrophic Cardiomyopathy
- 2- Obstructive Hypertrophic Cardiomyopathy
- 3- Non Obstructive Hypertrophic Cardiomyopathy
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | blood sample collection |
Timeline
- Start date
- 2009-04-01
- Primary completion
- 2013-12-01
- Completion
- 2013-12-01
- First posted
- 2012-11-20
- Last updated
- 2014-03-26
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT01729702. Inclusion in this directory is not an endorsement.