NCT01729078

Dietary Interventions in Prediabetes

The Effects of Dietary Supplementation on Hepatic Insulin Action and Glucose Tolerance in Pre-diabetes

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Assessment of glucose metabolism and liver fat after 12 week dietary intervention in pre diabetes subjects. Subjects will be randomized to either high fat (olive oil supplemented),high carb/high fiber (beans supplemented) and high carb/low fiber diets. Glucose metabolism will be assessed by labeled oral glucose tolerance test and liver fat by magnetic resonance spectroscopy pre randomization and at 8 and 12 week after starting dietary intervention.

Conditions

• Impaired Fasting Glucose
• Pre Diabetes
• Liver Fat

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Dietary intervention	three different diets ( high fat-low carb-low fiber/high carb-low fat - high fiber/high carb-low fat-low fiber)

Timeline

• Start date: 2012-10-01
• Primary completion: 2013-10-01
• Completion: 2014-02-01
• First posted: 2012-11-20
• Last updated: 2015-07-29

Locations

1 site across 1 country: United States