NCT01728402

Pathogenesis of Hematologic Malignancies

Pathogenesis of Acute Leukemia, Lymphoproliferative Disorders, and Myeloproliferative Disorders

• Status: Enrolling By Invitation
• Phase: —
• Study type: Observational
• Enrollment: 5,000 (estimated)
• Sponsor: OHSU Knight Cancer Institute · Academic / Other
• Sex: All
• Age: 1 Year
• Healthy volunteers: Not accepted

Summary

The cause of blood and bone marrow cancers is poorly understood; however, most research focuses on how cancer cells grow and develop. Because the causes of these cancers are unknown, current treatments may be unnecessarily harsh and often do not provide a cure. Identifying the causes of blood cancers would allow for the development of treatments that are more likely to provide a cure. To find the causes of blood and bone marrow cancers, we will look for specific cancer cell abnormalities that are responsible for cancer cell growth. We will then look to see if drugs that can reverse these abnormalities can kill cancer cells.

Conditions

• Acute Leukemia
• Lymphoproliferative Disorders
• Myeloproliferative Disorders
• Myelodysplastic Syndromes

Interventions

Type	Name	Description
PROCEDURE	blood draw, bone marrow procedure, or tissue biopsy

Timeline

• Start date: 2008-09-01
• First posted: 2012-11-19
• Last updated: 2026-02-17

Locations

1 site across 1 country: United States