Clinical Trials Directory

Trials / Terminated

TerminatedNCT01728116

Safety and Efficacy of EndoBarrier in Subjects With Type 2 Diabetes Who Are Obese

A Randomized, Multi-Center, Pivotal Efficacy and Safety Study Comparing the EndoBarrier Gastrointestinal Liner System vs. Sham for Glycemic Improvement in Inadequately Controlled Obese Type 2 Diabetic Subjects on Oral Anti-Diabetes Agents

Status
Terminated
Phase
N/A
Study type
Interventional
Enrollment
325 (actual)
Sponsor
Morphic Medical Inc. · Industry
Sex
All
Age
21 Years – 65 Years
Healthy volunteers
Not accepted

Summary

To determine if the EndoBarrier safely and effectively improves glycemic control in obese subjects with type 2 diabetes

Detailed description

This is a randomized, double blinded, prospective study. Subjects will be evaluated and randomized to either the device or sham treatment group if they qualify for the study. A comparison of glycemic control between the two groups will be assessed as the primary outcome measurement as well as the safety profile of the device.

Conditions

Interventions

TypeNameDescription
DEVICEEndoBarrierEndoscopically-delivered and removable device comprised of an anchor that is placed in the duodenal bulb and a 60 cm long impermeable liner that passes distal from the anchor point
PROCEDURESham ProcedureEndoscopic evaluation but no device placement

Timeline

Start date
2012-12-01
Primary completion
2016-02-01
Completion
2016-02-01
First posted
2012-11-16
Last updated
2017-02-01
Results posted
2016-12-02

Locations

25 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01728116. Inclusion in this directory is not an endorsement.