NCT01725607

Postoperative Sleep Quality in Patients Undergoing Thoracic Surgery With Different Types of Anesthesia Management

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 219 (actual)
• Sponsor: China Medical University, China · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

We designed a study to determine whether a single dose of dexmedetomidine or thoracic epidural anesthesia combined with general anesthesia would provide hemodynamic stability, reduce stress hormone responses, inhibit inflammatory cytokine secretion, and improve sleep quality in patients after thoracic surgery.

Detailed description

We designed a prospective, single-blinded, randomized, and controlled study to determine whether a single dose of dexmedetomidine or thoracic epidural anesthesia combined with general anesthesia would provide hemodynamic stability, reduce stress hormone responses, inhibit inflammatory cytokine secretion, and improve sleep quality in patients after thoracic surgery.

Conditions

• General Anesthesia, Thoracic Epidural Anesthesia

Interventions

Type	Name	Description
DRUG	general anesthesia combined with dexmedetomidine infusion	general anesthesia combined with 1 μg/kg dexmedetomidine infusion after induction (Group D)
PROCEDURE	general anesthesia combined with TEA	general anesthesia combined with TEA (Group E)

Timeline

• Start date: 2013-01-01
• Primary completion: 2014-02-01
• Completion: 2014-03-01
• First posted: 2012-11-14
• Last updated: 2015-07-08

Locations

1 site across 1 country: China