Trials / Completed
CompletedNCT01724892
Comparison the Effects of Dexamethasone and Loteprednol on Epithelial Healing
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 32 (actual)
- Sponsor
- Khon Kaen University · Academic / Other
- Sex
- All
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Not accepted
Summary
Corticosteroid has been used for the treatment after phototherapeutic keratectomy (PRK). Dexamethasone, a potent steroid can retard the corneal epithelial healing rate and has numerous serious complications, especially glaucoma. Loteprednol, a new generation of corticosteroid has less potency than dexamethasone and was proposed to has less side effect regarding intraocular pressure (IOP) elevation. Therefore, Investigators would like to compare the effect of dexamethasone and loteprednol on corneal epithelial healing rate after PRK and risk of glaucoma.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Dexamethasone | |
| DRUG | Loteprednol etabonate |
Timeline
- Start date
- 2012-11-01
- Primary completion
- 2013-09-01
- Completion
- 2013-09-01
- First posted
- 2012-11-12
- Last updated
- 2014-03-17
Locations
2 sites across 1 country: Thailand
Source: ClinicalTrials.gov record NCT01724892. Inclusion in this directory is not an endorsement.