NCT01723059

Standard Triple Therapy vs Sequential Therapy in Treatment of H Pylori Infection

Conventional Therapy vs Sequential Therapy for the Treatment of Helicobacter Pylori Infection

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 184 (estimated)
• Sponsor: Dallas VA Medical Center · Federal
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Accepted

Summary

Traditionally, H pylori infection has been treated with conventional triple therapy. This includes amoxicillin, clarithromycin and a proton pump inhibitor all given daily for 10-14 days. In Europe, the guidelines now advocate treatment of H pylori with sequential therapy which is 5 days of amoxicillin therapy with proton pump inhibitor followed by 5 days of clarithromycin, metronidazole, and proton pump inhibitor with better response rates. We hypothesize that H. pylori resistance pattern and treatment response rates observed in Europe will not be predictive of resistance patterns and response rates in the United States.

Conditions

• Helicobacter Infection

Interventions

Type	Name	Description
DRUG	Standard Triple Therapy	for 10 days
DRUG	Sequential Therapy	total 10 days

Timeline

• Start date: 2012-02-01
• Primary completion: 2013-01-01
• Completion: 2013-01-01
• First posted: 2012-11-07
• Last updated: 2012-11-07

Locations

1 site across 1 country: United States