Clinical Trials Directory

Trials / Completed

CompletedNCT01721746

A Study to Compare BMS-936558 to the Physician's Choice of Either Dacarbazine or Carboplatin and Paclitaxel in Advanced Melanoma Patients That Have Progressed Following Anti-CTLA-4 Therapy (CheckMate 037)

A Randomized Open-Label Phase 3 Trial of BMS-936558 (Nivolumab) Versus Investigator's Choice in Advanced (Unresectable or Metastatic) Melanoma Patients Progressing Post Anti-CTLA-4 Therapy

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
405 (actual)
Sponsor
Bristol-Myers Squibb · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to estimate the response rate and compare overall survival of patients taking BMS-936558 to those taking study physician's choice of either Dacarbazine or Carboplatin and Paclitaxel

Conditions

Interventions

TypeNameDescription
BIOLOGICALBMS-936558
DRUGDacarbazine
DRUGCarboplatin
DRUGPaclitaxel

Timeline

Start date
2012-12-21
Primary completion
2016-02-16
Completion
2020-12-29
First posted
2012-11-06
Last updated
2022-04-19
Results posted
2017-03-22

Locations

95 sites across 14 countries: United States, Austria, Belgium, Brazil, Canada, Denmark, France, Germany, Israel, Italy, Netherlands, Spain, Switzerland, United Kingdom

Source: ClinicalTrials.gov record NCT01721746. Inclusion in this directory is not an endorsement.