Trials / Completed
CompletedNCT01721460
Effects of Dexmedetomidine on Activity in the Subthalamic Nucleus
Effects of Dexmedetomidine on Neuronal Activity in the Subthalamic Nucleus During Deep Brain Stimulation (DBS) Electrode Implantation Surgery
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 6 (actual)
- Sponsor
- University of Wisconsin, Madison · Academic / Other
- Sex
- All
- Age
- 18 Years – 85 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this research study is to find out whether dexmedetomidine changes brain cell activity in the subthalamic nucleus (STN).
Detailed description
In order to find whether dexmedetomidine is optimal for sedation during Deep brain stimulation surgery, we will measure the electrical activity in the STN during Deep brain stimulation surgery, and measure how this activity is changed during administration of Dexmedetomidine. We hypothesize that dexmedetomidine does not change the firing rate and pattern in the STN.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Dexmedetomidine | Dexmedetomidine infusion will be started with a loading dose of 1 mcg/Kg over ten to 20 minutes followed by a maintenance infusion of 0.7 mcg/Kg/hr until stable sedation is achieved. |
Timeline
- Start date
- 2012-11-01
- Primary completion
- 2015-06-01
- Completion
- 2015-06-01
- First posted
- 2012-11-05
- Last updated
- 2017-12-08
- Results posted
- 2017-11-06
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01721460. Inclusion in this directory is not an endorsement.