NCT01720940

Reducing Nephrotoxicity of Vancomycin: A Prospective Study of Continuous Versus Intermittent Infusion of Vancomycin

Reducing Nephrotoxicity of Vancomycin: A Prospective, Randomized Study of Continuous Versus Intermittent Infusion of Vancomycin

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 220 (estimated)
• Sponsor: National University Hospital, Singapore · Academic / Other
• Sex: All
• Age: 21 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This study is being carried out to find out whether there is reduction in vancomycin-induced kidney injury (nephrotoxicity) when vancomycin is given as intermittent versus continuous infusion. This study will recruit 220 subjects from 2 hospitals over a period of 3 years. Participants are invited if they have an infection that requires prolonged vancomycin therapy (\> more than 10 days).

Conditions

• Infections Requiring Prolonged Duration (>10 Days) of Vancomycin

Interventions

Type	Name	Description
DRUG	continuous vancomycin infusion	24-hour continuous infusion of vancomycin
DRUG	intermittent vancomycin infusion

Timeline

• Start date: 2012-10-01
• Primary completion: 2015-09-01
• Completion: 2015-09-01
• First posted: 2012-11-02
• Last updated: 2012-11-02

Locations

1 site across 1 country: Singapore