NCT01719133

Skin Prick Tests With AllerT in Subjects Allergic to Birch Pollen

Détermination de la réactivité cutanée de Volontaires Allergiques au Pollen de Bouleau Contre Des Peptides dérivés de Bet v 1

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Anergis · Industry
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Assessment of skin reactivity by skin prick tests to synthetic peptides derived from the major birch allergen bet v 1, in subjects allergic to birch pollen.

Detailed description

The study tested - all by skin tests - in the same group of 20 trial subjects, one positive control (histamine solution), one negative control (placebo saline) and five experimental peptides called T1, T2, T3, T4 and T5. Results of the skin prick tests were scored as negative (no reaction) or positive (wheal diameter \> 4 mm with erythema)

Conditions

• Allergic Rhinitis

Interventions

Type	Name	Description
DRUG	placebo	saline solution
DRUG	Histamine	positive control
DRUG	AllerT1	synthetic peptide T1
DRUG	AllerT2	synthetic peptide T2
DRUG	AllerT3	synthetic peptide T3
DRUG	AllerT4	synthetic peptide T4
DRUG	AllerT5	synthetic peptide T5
DRUG	mix of AllerT1-T2-T3	mix of peptides T1, T2 and T3
DRUG	mix of AllerT4-T5	mix T4-T5

Timeline

• Start date: 2008-02-01
• Primary completion: 2008-03-01
• Completion: 2008-06-01
• First posted: 2012-11-01
• Last updated: 2012-11-01

Locations

1 site across 1 country: Switzerland