NCT01718925

25-hydroxyvitamin D and Fatigue: The VITALITY Study

Vitamin D, Fatigue and Patient Reported Outcome (PRO) in Chronic Somatic and Functional Disorders.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 614 (actual)
• Sponsor: Ostfold Hospital Trust · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The burden of chronic disease is continuing to rise. Even though patients may be in remission or have quiescent disease, several studies have confirmed that symptoms, such as e.g., fatigue, is troublesome. The primary aim of this study is to investigate whether or not there might be an association between levels of vitamin D and the subjective experience of fatigue in conditions, such as inflammatory bowel disease, diabetes mellitus, rheumatoid arthritis and irritable bowel syndrome. Secondary aims is to study both the co-occurence and influence of pain, depression and anxiety.

Detailed description

The burden of chronic disease is continuing to rise. Even though patients may be in remission or have quiescent disease, several studies have confirmed that symptoms, such as e.g., fatigue, is troublesome.Previous studies have confirmed that vitamin D deficiency is associated with both Crohn's disease and Rheumatoid Arthritis. Since Vitamin D is associated with both onset of chronic disease and energy, we aim in this study to assess its impact on fatigue in various chronic diseases. The primary aim of this study is to investigate whether or not there might be an association between levels of vitamin D and the subjective experience of fatigue in conditions, such as inflammatory bowel disease, diabetes mellitus, rheumatoid arthritis and irritable bowel syndrome. Secondary aims is to study both the co-occurence and influence of pain, depression and anxiety.

Conditions

• Irritable Bowel Syndrome
• Inflammatory Bowel Disease
• Diabetes
• Rheumatoid Arthritis

Timeline

• Start date: 2012-10-01
• Primary completion: 2014-11-01
• Completion: 2014-12-01
• First posted: 2012-11-01
• Last updated: 2015-10-15