NCT01712295

17% Salicylate Versus 17% Salicylate-Ethyl Pyruvate for Plantar Foot Warts

New Formulation of Salicylate to Improve Treatment of Common Skin Warts

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Grossman, Michael, D.P.M. · Individual
• Sex: All
• Age: 12 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Plantar warts on the sole of the foot are among the most common warts seen in podiatry clinics. Some patients are readily cured by simple standard of care treatments that include wart debridement (trimming or excision) and application of 17% salicylate (commercially known as Compound W)or by other treatments that may be painful and affect mobility. No treatment is consistently effective and most patients fail treatment multiple times. Ethyl pyruvate (EP)is a common food additive noted to be 'generally regarded as safe' that may improve the activity of salicylate in wart treatment by improving the ability to penetrate and/or persist in the skin. The use of 17% salicylate with the addition of EP may improve cures of common foot plantar warts in subjects who also be receiving other standard-of-care treatment.

Conditions

• Warts

Interventions

Type	Name	Description
DRUG	17% Salicylate with ethyl pyruvate
DRUG	Salicylates

Timeline

• Start date: 2011-11-01
• Primary completion: 2013-12-01
• Completion: 2014-03-01
• First posted: 2012-10-23
• Last updated: 2012-10-23

Locations

1 site across 1 country: United States