NCT01710696

Induction of Puberty With 17-beta Estradiol in Girls With Turner Syndrome

Induction of Puberty With 17-Beta Estradiol in Girls With Turner Syndrome. An Open Randomized Trial

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Novo Nordisk A/S · Industry
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

This trial is conducted in Europe. The aim of the trial is to induce normal pubertal development in girls with Turner Syndrome in accordance with that of their peers and their individual state psychosocial maturation.

Conditions

• Genetic Disorder
• Turner Syndrome

Interventions

Type	Name	Description
DRUG	17-beta estradiol	5-15 mcg/kg daily for 2 years. Dose readjusted every 3 months. Administered orally
DRUG	17-beta estradiol	0.2 mcg daily for 12 months, dose escalated to 0.5 mcg daily for 12 months. Administered orally

Timeline

• Start date: 1998-07-23
• Primary completion: 2004-07-26
• Completion: 2004-07-26
• First posted: 2012-10-19
• Last updated: 2017-02-28

Locations

28 sites across 1 country: Spain