NCT01709773

Focal Ablation of Cervical Precancer

Focal Ablation of High-grade Cervical Intraepithelial Neoplasia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University of California, San Francisco · Academic / Other
• Sex: Female
• Age: 21 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

This is a pilot cohort study of women undergoing focal ablation for high-grade cervical intraepithelial neoplasia (HGCIN). The cohort was recruited from the UCSF Dysplasia Clinics. The standard treatment involves treatment of the entire cervix. Women with HGCIN meeting inclusion criteria were recruited for enrollment into the pilot study of focal treatment. Upon enrollment, they underwent focal ablational treatment rather than standard ablational treatment of the cervix. Follow-up visits were conducted at 2 weeks and 6 months to assess safety, feasibility, and acceptability. The 6-month recurrence rate of HGCIN will be calculated.

Conditions

• High-grade Cervical Intraepithelial Neoplasia

Interventions

Type	Name	Description
PROCEDURE	Focal treatment	Focal treatment of high-grade cervical intraepithelial neoplasia using laser ablation, cryotherapy, or loop electrosurgical excision procedure

Timeline

• Start date: 2013-01-17
• Primary completion: 2014-04-11
• Completion: 2014-05-26
• First posted: 2012-10-18
• Last updated: 2018-02-20

Locations

1 site across 1 country: United States