Clinical Trials Directory

Trials / Completed

CompletedNCT01706679

Evaluation of the Effect of ATX-101 on QT/QTc Intervals

A Four-Arm, Parallel Design, Randomized, Double-Blinded, Placebo and Active Controlled Study for the Evaluation of the Effect of Maximum Therapeutic and Supratherapeutic Single-Dose ATX-101 on the QT/QTc Intervals in Healthy Volunteers

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
218 (actual)
Sponsor
Kythera Biopharmaceuticals · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

To evaluate the effect of maximum therapeutic and supratherapeutic doses of ATX-101 treatment on Fridericia's corrected QT interval (QTcF).

Conditions

Interventions

TypeNameDescription
DRUGATX-101 (10 mg/ml)
DRUGATX-101 (20 mg/ml)
DRUGMoxifloxacin (400 mg)
DRUGPlacebo vehicle (PBS)

Timeline

Start date
2012-10-01
Primary completion
2013-02-01
Completion
2013-06-01
First posted
2012-10-15
Last updated
2013-11-14

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01706679. Inclusion in this directory is not an endorsement.